Richard Knox

Opportunists who market street drugs may be undermining the global struggle against AIDS.

In South Africa, two mainstay HIV drugs have found their way into recreational use. That may help explain why some HIV patients are resistant to these front-line medicines even if they've never been in treatment before.

It can happen in two ways.

Boston brain surgeon Ed Smith points to a tangle of delicate gray shadows on his computer screen. It's an X-ray of the blood vessels on the left side of 13-year-old Maribel Ramos' brain.

The World Health Organization says a new coronavirus has killed two people in Jordan — the third country where the novel microbe has been traced.

That brings lab-confirmed cases to nine, with five fatalities.

Before Secretary of State Hilary Rodham Clinton passes the reins to her successor, she's got a few loose ends to tie up. One of them is mapping out the U.S.'s continuing efforts to combat AIDS around the world.

So today she unveiled a "blueprint" for what she called an "AIDS-free generation."

Now Clinton isn't talking about ending the HIV pandemic altogether. Rather, she hopes to prevent most new infections from occurring in the first place and to stop HIV-positive people from developing AIDS.

It's a startling trend: Many women with cancer in one breast are choosing to have their healthy breast removed, too.

But a study being presented later this week says more than three-quarters of women who opt for double mastectomies are not getting any benefit because their risk of cancer developing in the healthy breast is no greater than in women without cancer.

The endless debate over routine mammograms is getting another kick from an analysis that sharply questions whether the test really does what it's supposed to.

Dr. H. Gilbert Welch, coauthor of the analysis of mammography's impact, which was just published in The New England Journal of Medicine, tell Shots that the aim was to "get down to a very basic question."

The public health world has waited for the results for more than a year. After a half-billion dollars in R&D, would the front-runner malaria vaccine protect the top-priority targets: young infants?

The results are disappointing. The vaccine — called RTS,S for its various molecular components — reduced infants' risk of malaria by about a third.

The news for patients who had injections of fungus-tainted steroids just keeps getting worse.

One lasting image of Superstorm Sandy will be very sick patients being evacuated from flooded hospitals. But less visible are thousands of patients who rely on visiting nurses and home health aides for care ranging from bathing and feeding to oxygen and ventilators.

Hurricane Sandy only sideswiped Haiti during its early days. But reports so far suggest that even this indirect hit led to nearly as many deaths there as in the U.S. after the storm made landfall on the Mid-Atlantic coast.

As of Wednesday, Haiti had documented 54 deaths caused by Sandy — most in the nation's southern peninsula, which points toward Jamaica. Another 21 Haitians were still counted as missing, and many fear the death toll will rise as officials reach affected areas isolated by impassable roads and ruined bridges.